Pyrrolizidine alkaloid-induced transcriptomic changes in rat lungs in a 28-day subacute feeding study

Pyrrolizidine alkaloids (PAs) are secondary plant metabolites synthesized by a wide range of plants as protection against herbivores. These toxins are found worldwide and pose a threat to human health. PAs induce acute effects like hepatic sinusoidal obstruction syndrome and pulmonary arterial hyper...

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Detalhes bibliográficos
Publicado no:Arch Toxicol
Main Authors: Buchmueller, Julia, Sprenger, Heike, Ebmeyer, Johanna, Rasinger, Josef Daniel, Creutzenberg, Otto, Schaudien, Dirk, Hengstler, Jan G., Guenther, Georgia, Braeuning, Albert, Hessel-Pras, Stefanie
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2021
Assuntos:
Organ Toxicity and Mechanisms
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8298252/
https://ncbi.nlm.nih.gov/pubmed/34185104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-021-03108-x
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