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Pyrrolizidine Alkaloids Disturb Bile Acid Homeostasis in the Human Hepatoma Cell Line HepaRG

1,2-unsaturated pyrrolizidine alkaloids (PAs) belong to a group of secondary plant metabolites. Exposure to PA-contaminated feed and food may cause severe hepatotoxicity. A pathway possibly involved in PA toxicity is the disturbance of bile acid homeostasis. Therefore, in this study, the influence o...

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Bibliografische gegevens
Gepubliceerd in:Foods
Hoofdauteurs: Waizenegger, Julia, Glück, Josephin, Henricsson, Marcus, Luckert, Claudia, Braeuning, Albert, Hessel-Pras, Stefanie
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7828834/
https://ncbi.nlm.nih.gov/pubmed/33466663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/foods10010161
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