Hepatotoxic pyrrolizidine alkaloids induce DNA damage response in rat liver in a 28-day feeding study

Pyrrolizidine alkaloids (PA) are secondary plant metabolites that occur as food and feed contaminants. Acute and subacute PA poisoning can lead to severe liver damage in humans and animals, comprising liver pain, hepatomegaly and the development of ascites due to occlusion of the hepatic sinusoids (...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Arch Toxicol
Päätekijät: Ebmeyer, Johanna, Rasinger, Josef Daniel, Hengstler, Jan G., Schaudien, Dirk, Creutzenberg, Otto, Lampen, Alfonso, Braeuning, Albert, Hessel-Pras, Stefanie
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer Berlin Heidelberg 2020
Aiheet:
Organ Toxicity and Mechanisms
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7261731/
https://ncbi.nlm.nih.gov/pubmed/32419051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-020-02779-2
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia