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Deglycase-activity oriented screening to identify DJ-1 inhibitors
The oncoprotein and Parkinson's disease-associated enzyme DJ-1/PARK7 has emerged as a promiscuous deglycase that can remove methylglyoxal-induced glycation adducts from both proteins and nucleotides. However, dissecting its structural and enzymatic functions remains a challenge due to the lack...
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| Izdano u: | RSC Med Chem |
|---|---|
| Glavni autori: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
RSC
2021
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8292988/ https://ncbi.nlm.nih.gov/pubmed/34355187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d1md00062d |
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