GSDMD-Mediated Cardiomyocyte Pyroptosis Promotes Myocardial I/R Injury

RATIONALE: Pyroptosis is a morphologically and mechanistically distinct form of cell death and is characterized by GSDMD (gasdermin D) or GSDME (gasdermin E)-mediated necrosis with excessive inflammatory factor release. Cardiomyocyte necrosis and inflammation play key roles in the pathophysiology of...

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Detalhes bibliográficos
Publicado no:Circ Res
Main Authors: Shi, Huairui, Gao, Yang, Dong, Zhen, Yang, Ji’e, Gao, Rifeng, Li, Xiao, Zhang, Shuqi, Ma, Leilei, Sun, Xiaolei, Wang, Zeng, Zhang, Feng, Hu, Kai, Sun, Aijun, Ge, Junbo
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2021
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8291144/
https://ncbi.nlm.nih.gov/pubmed/34015941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.120.318629
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