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Mitochondrial GSDMD Pores DAMPen Pyroptosis

Noncanoncial inflammasome activation by cytosolic lipopolysaccharide (LPS) causes pyroptotic cell death facilitated by gasdermin D (GSDMD) pore formation. In this issue of Immunity, Huang et al. describe how cytosolic LPS in endothelial cells does not cause cell death but restrains endothelial cell...

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Publicat a:Immunity
Autors principals: Barnett, Katherine C., Ting, Jenny P.-Y.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7337261/
https://ncbi.nlm.nih.gov/pubmed/32187511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2020.02.012
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