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Mitochondrial GSDMD Pores DAMPen Pyroptosis
Noncanoncial inflammasome activation by cytosolic lipopolysaccharide (LPS) causes pyroptotic cell death facilitated by gasdermin D (GSDMD) pore formation. In this issue of Immunity, Huang et al. describe how cytosolic LPS in endothelial cells does not cause cell death but restrains endothelial cell...
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| Publicado no: | Immunity |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7337261/ https://ncbi.nlm.nih.gov/pubmed/32187511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2020.02.012 |
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