GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes

Gasdermin-D (GsdmD) is a critical mediator of innate immune defense because its cleavage by the inflammatory caspases 1, 4, 5, and 11 yields an N-terminal p30 fragment that induces pyroptosis, a death program important for the elimination of intracellular bacteria. Precisely how GsdmD p30 triggers p...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Aglietti, Robin A., Estevez, Alberto, Gupta, Aaron, Ramirez, Monica Gonzalez, Liu, Peter S., Kayagaki, Nobuhiko, Ciferri, Claudio, Dixit, Vishva M., Dueber, Erin C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2016
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948338/
https://ncbi.nlm.nih.gov/pubmed/27339137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1607769113
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia