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Chopping GSDMD: caspase‐8 has joined the team of pyroptosis‐mediating caspases
nflammatory and apoptotic caspases mediate two distinct forms of cell death: pyroptosis and apoptosis, respectively. Three independent studies have now demonstrated that the “apoptotic” caspase‐8 can cleave gasdermin D (GSDMD) leading to pyroptosis‐like cell death and IL‐1β release in murine macroph...
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| Publicado no: | EMBO J |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6517822/ https://ncbi.nlm.nih.gov/pubmed/30988015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019102065 |
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