Essential role for Gata2 in modulating lineage output from hematopoietic stem cells in zebrafish

The differentiation of hematopoietic stem cells (HSCs) is tightly controlled to ensure a proper balance between myeloid and lymphoid cell output. GATA2 is a pivotal hematopoietic transcription factor required for generation and maintenance of HSCs. GATA2 is expressed throughout development, but beca...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Gioacchino, Emanuele, Koyunlar, Cansu, Zink, Joke, de Looper, Hans, de Jong, Madelon, Dobrzycki, Tomasz, Mahony, Christopher B., Hoogenboezem, Remco, Bosch, Dennis, van Strien, Paulina M. H., van Royen, Martin E., French, Pim J., Bindels, Eric, Gussinklo, Kirsten J., Monteiro, Rui, Touw, Ivo P., de Pater, Emma
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2021
Assuntos:
Hematopoiesis and Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8288679/
https://ncbi.nlm.nih.gov/pubmed/34170285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002993
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