Essential role for Gata2 in modulating lineage output from hematopoietic stem cells in zebrafish

The differentiation of hematopoietic stem cells (HSCs) is tightly controlled to ensure a proper balance between myeloid and lymphoid cell output. GATA2 is a pivotal hematopoietic transcription factor required for generation and maintenance of HSCs. GATA2 is expressed throughout development, but beca...

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Udgivet i:Blood Adv
Main Authors: Gioacchino, Emanuele, Koyunlar, Cansu, Zink, Joke, de Looper, Hans, de Jong, Madelon, Dobrzycki, Tomasz, Mahony, Christopher B., Hoogenboezem, Remco, Bosch, Dennis, van Strien, Paulina M. H., van Royen, Martin E., French, Pim J., Bindels, Eric, Gussinklo, Kirsten J., Monteiro, Rui, Touw, Ivo P., de Pater, Emma
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2021
Fag:
Hematopoiesis and Stem Cells
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8288679/
https://ncbi.nlm.nih.gov/pubmed/34170285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002993
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