Gut microbes impact stroke severity via the trimethylamine-N-oxide pathway

Clinical studies demonstrate associations between circulating levels of the gut microbiota derived metabolite trimethylamine-N-oxide (TMAO) and incident stroke risks. However, a causal role of gut microbes in stroke has not yet been demonstrated. Herein we show that gut microbes, through dietary cho...

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發表在:Cell Host Microbe
Main Authors: Zhu, Weifei, Romano, Kymberleigh A., Li, Lin, Buffa, Jennifer A., Sangwan, Naseer, Prakash, Prem, Tittle, Aaron N., Li, Xinmin S., Fu, Xiaoming, Androjna, Charlie, DiDonato, Anthony J., Brinson, Kimberly, Trapp, Bruce D., Fischbach, Michael A., Rey, Federico E., Hajjar, Adeline M., DiDonato, Joseph A., Hazen, Stanley L.
格式: Artigo
語言:Inglês
出版: 2021
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8288076/
https://ncbi.nlm.nih.gov/pubmed/34139173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2021.05.002
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