Gut microbes impact stroke severity via the trimethylamine-N-oxide pathway

Clinical studies demonstrate associations between circulating levels of the gut microbiota derived metabolite trimethylamine-N-oxide (TMAO) and incident stroke risks. However, a causal role of gut microbes in stroke has not yet been demonstrated. Herein we show that gut microbes, through dietary cho...

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Gepubliceerd in:Cell Host Microbe
Hoofdauteurs: Zhu, Weifei, Romano, Kymberleigh A., Li, Lin, Buffa, Jennifer A., Sangwan, Naseer, Prakash, Prem, Tittle, Aaron N., Li, Xinmin S., Fu, Xiaoming, Androjna, Charlie, DiDonato, Anthony J., Brinson, Kimberly, Trapp, Bruce D., Fischbach, Michael A., Rey, Federico E., Hajjar, Adeline M., DiDonato, Joseph A., Hazen, Stanley L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2021
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8288076/
https://ncbi.nlm.nih.gov/pubmed/34139173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2021.05.002
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