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Non-lethal inhibition of gut microbial trimethylamine production for the treatment of atherosclerosis
Trimethylamine N-oxide (TMAO), a gut microbiota dependent metabolite, both enhances atherosclerosis in animal models and is associated with cardiovascular risks in clinical studies. Here we investigate the impact of targeted inhibition of the first step in TMAO generation, commensal microbial trimet...
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| Publicado no: | Cell |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4871610/ https://ncbi.nlm.nih.gov/pubmed/26687352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.11.055 |
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