Loop Diuretics Inhibit Renal Excretion of Trimethylamine N-Oxide

This study demonstrates, for the first time, that renal tubular excretion of trimethylamine N-oxide (TMAO) is inhibited by concomitant loop diuretic administration. The observed marked accumulation in the renal parenchyma, and to lesser extent, plasma, implies differential distributions of TMAO acro...

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Bibliografiske detaljer
Udgivet i:JACC Basic Transl Sci
Main Authors: Li, Daniel Y., Wang, Zeneng, Jia, Xun, Yan, Di, Shih, Diana M., Hazen, Stanley L., Lusis, Aldons J., Tang, W.H. Wilson
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2021
Fag:
Clinical Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7907536/
https://ncbi.nlm.nih.gov/pubmed/33665512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2020.11.010
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