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rigrag: high-resolution mapping of genic targeting preferences during HIV-1 integration in vitro and in vivo

HIV-1 integration favors recurrent integration gene (RIG) targets and genic proviruses can confer cell survival in vivo. However, the relationship between initial RIG integrants and how these evolve in patients over time are unknown. To address these shortcomings, we built phenomenological models of...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Bedwell, Gregory J, Jang, Sooin, Li, Wen, Singh, Parmit K, Engelman, Alan N
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8287940/
https://ncbi.nlm.nih.gov/pubmed/34165568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab514
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