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Cellular and molecular mechanisms of HIV-1 integration targeting

Integration is central to HIV-1 replication and helps mold the reservoir of cells that persists in AIDS patients. HIV-1 interacts with specific cellular factors to target integration to interior regions of transcriptionally active genes within gene-dense regions of chromatin. The viral capsid intera...

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Bibliografiske detaljer
Udgivet i:Cell Mol Life Sci
Main Authors: Engelman, Alan N., Singh, Parmit K.
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004233/
https://ncbi.nlm.nih.gov/pubmed/29417178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-018-2772-5
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