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Endonuclease enrichment TAPS for cost-effective genome-wide base-resolution DNA methylation detection

Whole genome base-resolution methylome sequencing allows for the most comprehensive analysis of DNA methylation, however, the considerable sequencing cost often limits its applications. While reduced representation sequencing can be an affordable alternative, over 80% of CpGs in the genome are not c...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Cheng, Jingfei, Siejka-Zielińska, Paulina, Liu, Yibin, Chandran, Anandhakumar, Kriaucionis, Skirmantas, Song, Chun-Xiao
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8287915/
https://ncbi.nlm.nih.gov/pubmed/33905495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab291
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