Accurate targeted long-read DNA methylation and hydroxymethylation sequencing with TAPS

We present long-read Tet-assisted pyridine borane sequencing (lrTAPS) for targeted base-resolution sequencing of DNA methylation and hydroxymethylation in regions up to 10 kb from nanogram-level input. Compatible with both Oxford Nanopore and PacBio Single-Molecule Real-Time (SMRT) sequencing, lrTAP...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Liu, Yibin, Cheng, Jingfei, Siejka-Zielińska, Paulina, Weldon, Carika, Roberts, Hannah, Lopopolo, Maria, Magri, Andrea, D’Arienzo, Valentina, Harris, James M., McKeating, Jane A., Song, Chun-Xiao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053107/
https://ncbi.nlm.nih.gov/pubmed/32127008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-01969-6
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