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BRAT-BW: efficient and accurate mapping of bisulfite-treated reads

Summary: We introduce BRAT-BW, a fast, accurate and memory-efficient tool that maps bisulfite-treated short reads (BS-seq) to a reference genome using the FM-index (Burrows–Wheeler transform). BRAT-BW is significantly more memory efficient and faster on longer reads than current state-of-the-art too...

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Main Authors: Harris, Elena Y., Ponts, Nadia, Le Roch, Karine G., Lonardi, Stefano
格式: Artigo
語言:Inglês
出版: Oxford University Press 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3381974/
https://ncbi.nlm.nih.gov/pubmed/22563065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts264
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