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YY1 control of mitochondrial-related genes does not account for regulation of immunoglobulin class switch recombination in mice

Immunoglobulin class switch recombination (CSR) occurs in activated B cells with increased mitochondrial mass and membrane potential. Transcription factor Yin Yang 1 (YY1) is critical for CSR and for formation of the DNA loops involved in this process. We therefore sought to determine if YY1 knockou...

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Veröffentlicht in:Eur J Immunol
Hauptverfasser: Nandi, Satabdi, Liang, Guanxiang, Sindhava, Vishal, Angireddy, Rajesh, Basu, Arindam, Banerjee, Sarmistha, Hodawadekar, Suchita, Zhang, Yue, Avadhani, Narayan G., Sen, Ranjan, Atchison, Michael L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8287517/
https://ncbi.nlm.nih.gov/pubmed/32092784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201948385
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