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Subtype-selective mechanisms of negative allosteric modulators binding to group I metabotropic glutamate receptors
Group I metabotropic glutamate receptors (mGlu(1) and mGlu(5)) are promising targets for multiple psychiatric and neurodegenerative disorders. Understanding the subtype selectivity of mGlu(1) and mGlu(5) allosteric sites is essential for the rational design of novel modulators with single- or dual-t...
Gorde:
| Argitaratua izan da: | Acta Pharmacol Sin |
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| Egile Nagusiak: | , , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Springer Singapore
2020
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8285414/ https://ncbi.nlm.nih.gov/pubmed/33122823 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-020-00541-z |
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