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Comprehensive functional evaluation of variants of fibroblast growth factor receptor genes in cancer
Various genetic alterations of the fibroblast growth factor receptor (FGFR) family have been detected across a wide range of cancers. However, inhibition of FGFR signaling by kinase inhibitors demonstrated limited clinical effectiveness. Herein, we evaluated the transforming activity and sensitivity...
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| Publicat a: | NPJ Precis Oncol |
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| Autors principals: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8285406/ https://ncbi.nlm.nih.gov/pubmed/34272467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41698-021-00204-0 |
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