First‐in‐human phase I study of E7090, a novel selective fibroblast growth factor receptor inhibitor, in patients with advanced solid tumors

Fibroblast growth factor receptors (FGFR) are a family of transmembrane receptor tyrosine kinases involved in regulating cellular processes. FGFR mutations are implicated in oncogenesis, representing therapeutic potential in the form of FGFR inhibitors. This phase I, first‐in‐human study in Japan ev...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancer Sci
Prif Awduron: Koyama, Takafumi, Shimizu, Toshio, Iwasa, Satoru, Fujiwara, Yutaka, Kondo, Shunsuke, Kitano, Shigehisa, Yonemori, Kan, Shimomura, Akihiko, Iizumi, Sakura, Sasaki, Tatsuya, Furuse, Junji, Yamamoto, Noboru
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2020
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7004556/
https://ncbi.nlm.nih.gov/pubmed/31797489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14265
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg