First‐in‐human phase I study of E7090, a novel selective fibroblast growth factor receptor inhibitor, in patients with advanced solid tumors

Fibroblast growth factor receptors (FGFR) are a family of transmembrane receptor tyrosine kinases involved in regulating cellular processes. FGFR mutations are implicated in oncogenesis, representing therapeutic potential in the form of FGFR inhibitors. This phase I, first‐in‐human study in Japan ev...

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Bibliographic Details
Published in:Cancer Sci
Main Authors: Koyama, Takafumi, Shimizu, Toshio, Iwasa, Satoru, Fujiwara, Yutaka, Kondo, Shunsuke, Kitano, Shigehisa, Yonemori, Kan, Shimomura, Akihiko, Iizumi, Sakura, Sasaki, Tatsuya, Furuse, Junji, Yamamoto, Noboru
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2020
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7004556/
https://ncbi.nlm.nih.gov/pubmed/31797489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14265
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