Integrated Polygenic Tool Substantially Enhances Coronary Artery Disease Prediction

BACKGROUND: There is considerable interest in whether genetic data can be used to improve standard cardiovascular disease risk calculators, as the latter are routinely used in clinical practice to manage preventative treatment. METHODS: Using the UK Biobank resource, we developed our own polygenic r...

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Dades bibliogràfiques
Publicat a:Circ Genom Precis Med
Autors principals: Riveros-Mckay, Fernando, Weale, Michael E., Moore, Rachel, Selzam, Saskia, Krapohl, Eva, Sivley, R. Michael, Tarran, William A., Sørensen, Peter, Lachapelle, Alexander S., Griffiths, Jonathan A., Saffari, Ayden, Deanfield, John, Spencer, Chris C.A., Hippisley-Cox, Julia, Hunter, David J., O’Sullivan, Jack W., Ashley, Euan A., Plagnol, Vincent, Donnelly, Peter
Format: Artigo
Idioma:Inglês
Publicat: Lippincott Williams & Wilkins 2021
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8284388/
https://ncbi.nlm.nih.gov/pubmed/33651632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGEN.120.003304
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