טוען...
Programmed cell death protein-1 (PD-1) protects liver damage by suppressing IFN-γ expression in T cells in infants and neonatal mice
BACKGROUND: Biliary atresia (BA) is a severe cholangiopathy possibly resulting from virus-induced and immune-mediated injury of the biliary system. IFN-γ, secreted from CD4(+) Th1 cells and CD8(+) cytotoxic T cells, is a major mediator of liver pathology. Programmed death protein-1 (PD-1) signaling...
שמור ב:
| הוצא לאור ב: | BMC Pediatr |
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| Main Authors: | , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
BioMed Central
2021
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8284022/ https://ncbi.nlm.nih.gov/pubmed/34271894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12887-021-02794-x |
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