Increase of cells expressing PD‐1 and PD‐L1 and enhancement of IFN‐γ production via PD‐1/PD‐L1 blockade in bovine mycoplasmosis

INTRODUCTION: Bovine mycoplasma, chiefly Mycoplasma bovis, is a pathogen that causes pneumonia, mastitis, arthritis, and otitis media in cattle. This pathogen exerts immunosuppressive effects, such as the inhibition of interferon production. However, the mechanisms involved in bovine mycoplasmosis h...

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Detalhes bibliográficos
Publicado no:Immun Inflamm Dis
Main Authors: Goto, Shinya, Konnai, Satoru, Okagawa, Tomohiro, Nishimori, Asami, Maekawa, Naoya, Gondaira, Satoshi, Higuchi, Hidetoshi, Koiwa, Masateru, Tajima, Motoshi, Kohara, Junko, Ogasawara, Satoshi, Kato, Yukinari, Suzuki, Yasuhiko, Murata, Shiro, Ohashi, Kazuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5569371/
https://ncbi.nlm.nih.gov/pubmed/28544524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.173
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