Mitochondrial mistranslation modulated by metabolic stress causes cardiovascular disease and reduced lifespan

Changes in the rate and fidelity of mitochondrial protein synthesis impact the metabolic and physiological roles of mitochondria. Here we explored how environmental stress in the form of a high‐fat diet modulates mitochondrial translation and affects lifespan in mutant mice with error‐prone (Mrps12(...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Aging Cell
Egile Nagusiak: Richman, Tara R., Ermer, Judith A., Siira, Stefan J., Kuznetsova, Irina, Brosnan, Christopher A., Rossetti, Giulia, Baker, Jessica, Perks, Kara L., Cserne Szappanos, Henrietta, Viola, Helena M., Gray, Nicola, Larance, Mark, Hool, Livia C., Zuryn, Steven, Rackham, Oliver, Filipovska, Aleksandra
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2021
Gaiak:
Original Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8282274/
https://ncbi.nlm.nih.gov/pubmed/34096683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13408
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