Stress signaling and cellular proliferation reverse the effects of mitochondrial mistranslation

Translation fidelity is crucial for prokaryotes and eukaryotic nuclear‐encoded proteins; however, little is known about the role of mistranslation in mitochondria and its potential effects on metabolism. We generated yeast and mouse models with error‐prone and hyper‐accurate mitochondrial translatio...

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Publicat a:EMBO J
Autors principals: Ferreira, Nicola, Perks, Kara L, Rossetti, Giulia, Rudler, Danielle L, Hughes, Laetitia A, Ermer, Judith A, Scott, Louis H, Kuznetsova, Irina, Richman, Tara R, Narayana, Vinod K, Abudulai, Laila N, Shearwood, Anne‐Marie J, Cserne Szappanos, Henrietta, Tull, Dedreia, Yeoh, George C, Hool, Livia C, Filipovska, Aleksandra, Rackham, Oliver
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6912024/
https://ncbi.nlm.nih.gov/pubmed/31721250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019102155
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