Stress signaling and cellular proliferation reverse the effects of mitochondrial mistranslation

Translation fidelity is crucial for prokaryotes and eukaryotic nuclear‐encoded proteins; however, little is known about the role of mistranslation in mitochondria and its potential effects on metabolism. We generated yeast and mouse models with error‐prone and hyper‐accurate mitochondrial translatio...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Ferreira, Nicola, Perks, Kara L, Rossetti, Giulia, Rudler, Danielle L, Hughes, Laetitia A, Ermer, Judith A, Scott, Louis H, Kuznetsova, Irina, Richman, Tara R, Narayana, Vinod K, Abudulai, Laila N, Shearwood, Anne‐Marie J, Cserne Szappanos, Henrietta, Tull, Dedreia, Yeoh, George C, Hool, Livia C, Filipovska, Aleksandra, Rackham, Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6912024/
https://ncbi.nlm.nih.gov/pubmed/31721250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019102155
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