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Ligation of newly replicated DNA controls the timing of DNA mismatch repair

Mismatch repair (MMR) safeguards genome stability through recognition and excision of DNA replication errors.(1–4) How eukaryotic MMR targets the newly replicated strand in vivo has not been established. MMR reactions reconstituted in vitro are directed to the strand containing a preexisting nick or...

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Detalhes bibliográficos
Publicado no:Curr Biol
Main Authors: Reyes, Gloria X., Kolodziejczak, Anna, Devakumar, Lovely Jael Paul Solomon, Kubota, Takashi, Kolodner, Richard D., Putnam, Christopher D., Hombauer, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8281387/
https://ncbi.nlm.nih.gov/pubmed/33417883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2020.12.018
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