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Mismatch repair, but not heteroduplex rejection, is temporally coupled to DNA replication
In eukaryotes, it is unknown if mismatch repair (MMR) is temporally coupled to DNA replication and how strand-specific MMR is directed. Here we fused Saccharomyces cerevisiae MSH6 with cyclins to restrict the availability of the Msh2-Msh6 mismatch recognition complex to either S-phase or G2/M. The M...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3806717/ https://ncbi.nlm.nih.gov/pubmed/22194578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1210770 |
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