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Ligation of newly replicated DNA controls the timing of DNA mismatch repair

Mismatch repair (MMR) safeguards genome stability through recognition and excision of DNA replication errors.(1–4) How eukaryotic MMR targets the newly replicated strand in vivo has not been established. MMR reactions reconstituted in vitro are directed to the strand containing a preexisting nick or...

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Vydáno v:Curr Biol
Hlavní autoři: Reyes, Gloria X., Kolodziejczak, Anna, Devakumar, Lovely Jael Paul Solomon, Kubota, Takashi, Kolodner, Richard D., Putnam, Christopher D., Hombauer, Hans
Médium: Artigo
Jazyk:Inglês
Vydáno: 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8281387/
https://ncbi.nlm.nih.gov/pubmed/33417883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2020.12.018
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