Phosphoproteomic identification of ULK substrates reveals VPS15‐dependent ULK/VPS34 interplay in the regulation of autophagy

Autophagy is a process through which intracellular cargoes are catabolised inside lysosomes. It involves the formation of autophagosomes initiated by the serine/threonine kinase ULK and class III PI3 kinase VPS34 complexes. Here, unbiased phosphoproteomics screens in mouse embryonic fibroblasts dele...

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Pubblicato in:EMBO J
Autori principali: Mercer, Thomas John, Ohashi, Yohei, Boeing, Stefan, Jefferies, Harold B J, De Tito, Stefano, Flynn, Helen, Tremel, Shirley, Zhang, Wenxin, Wirth, Martina, Frith, David, Snijders, Ambrosius P, Williams, Roger Lee, Tooze, Sharon A
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2021
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8280838/
https://ncbi.nlm.nih.gov/pubmed/34121209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020105985
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