Membrane characteristics tune activities of endosomal and autophagic human VPS34 complexes

The lipid kinase VPS34 orchestrates diverse processes, including autophagy, endocytic sorting, phagocytosis, anabolic responses and cell division. VPS34 forms various complexes that help adapt it to specific pathways, with complexes I and II being the most prominent ones. We found that physicochemic...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Ohashi, Yohei, Tremel, Shirley, Masson, Glenn Robert, McGinney, Lauren, Boulanger, Jerome, Rostislavleva, Ksenia, Johnson, Christopher M, Niewczas, Izabella, Clark, Jonathan, Williams, Roger L
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2020
Fag:
Biochemistry and Chemical Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7326497/
https://ncbi.nlm.nih.gov/pubmed/32602837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.58281
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