Membrane characteristics tune activities of endosomal and autophagic human VPS34 complexes

The lipid kinase VPS34 orchestrates diverse processes, including autophagy, endocytic sorting, phagocytosis, anabolic responses and cell division. VPS34 forms various complexes that help adapt it to specific pathways, with complexes I and II being the most prominent ones. We found that physicochemic...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:eLife
Prif Awduron: Ohashi, Yohei, Tremel, Shirley, Masson, Glenn Robert, McGinney, Lauren, Boulanger, Jerome, Rostislavleva, Ksenia, Johnson, Christopher M, Niewczas, Izabella, Clark, Jonathan, Williams, Roger L
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: eLife Sciences Publications, Ltd 2020
Pynciau:
Biochemistry and Chemical Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7326497/
https://ncbi.nlm.nih.gov/pubmed/32602837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.58281
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