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The Genetic and Clinical Significance of Fetal Hemoglobin Expression in Sickle Cell Disease
Sickle cell disease (SCD) is phenotypically heterogeneous. One major genetic modifying factor is the patient's fetal hemoglobin (HbF) level. The latter is determined by the patient's β-globin gene cluster haplotype and cis- and trans-acting single nucleotide polymorphisms (SNPs) at other d...
Gardado en:
| Publicado en: | Med Princ Pract |
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| Autor Principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
S. Karger AG
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8280415/ https://ncbi.nlm.nih.gov/pubmed/32892201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000511342 |
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