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Mechanism and Origins of Stereoselectivity of the Aldol-Tishchenko Reaction of Sulfinimines

[Image: see text] Density functional theory computations have elucidated the mechanism and origins of stereoselectivity in McGlacken’s aldol-Tishchenko reaction for the diastereoselective synthesis of 1,3-amino alcohols using Ellman’s t-butylsulfinimines as chiral auxiliaries. Variations of stereoch...

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Detalhes bibliográficos
Publicado no:J Org Chem
Main Authors: Turlik, Aneta, Ando, Kaori, Mackey, Pamela, Alcock, Emma, Light, Mark, McGlacken, Gerard P., Houk, K. N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2021
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8279497/
https://ncbi.nlm.nih.gov/pubmed/33586983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.0c02862
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