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Synthesis of Natural (−)-Antrocin and Its Enantiomer via Stereoselective Aldol Reaction
The total synthesis of (−)-antrocin and its enantiomer are presented. Antrocin (−)-1 is an important natural product which acts as an antiproliferative agent in a metastatic breast cancer cell line (IC(50): 0.6 μM). The key features of this synthesis are: (a) selective anti-addition of trimethylsily...
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| Publicat a: | Molecules |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7070359/ https://ncbi.nlm.nih.gov/pubmed/32075004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25040831 |
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