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Computational investigations of the stereoselectivities of proline-related catalysts for aldol reactions

Computational investigation of the aldol reaction of benzaldehyde with acetone catalyzed by various proline derivatives and 2-azetidine carboxylic acid reveal the origins of stereoselectivities of these reactions. Structural differences between catalysts and transition states were analyzed with dens...

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Autores principales: Allemann, Christophe, Um, Joann M., Houk, K. N.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902180/
https://ncbi.nlm.nih.gov/pubmed/20634993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcata.2010.03.020
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