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Hydrophobic Substituent Effects on Proline Catalysis of Aldol Reactions in Water
[Image: see text] Derivatives of 4-hydroxyproline with a series of hydrophobic groups in well-defined orientations have been tested as catalysts for the aldol reactions. All of the modified proline catalysts carry out the intermolecular aldol reaction in water and provide high diastereoselectivity a...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3589585/ https://ncbi.nlm.nih.gov/pubmed/22500641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo300569c |
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