Gene–Environment Interactions in Developmental Neurotoxicity: a Case Study of Synergy between Chlorpyrifos and CHD8 Knockout in Human BrainSpheres

BACKGROUND: Autism spectrum disorder (ASD) is a major public health concern caused by complex genetic and environmental components. Mechanisms of gene–environment ([Formula: see text]) interactions and reliable biomarkers associated with ASD are mostly unknown or controversial. Induced pluripotent s...

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Dettagli Bibliografici
Pubblicato in:Environ Health Perspect
Autori principali: Modafferi, Sergio, Zhong, Xiali, Kleensang, Andre, Murata, Yohei, Fagiani, Francesca, Pamies, David, Hogberg, Helena T., Calabrese, Vittorio, Lachman, Herbert, Hartung, Thomas, Smirnova, Lena
Natura: Artigo
Lingua:Inglês
Pubblicazione: Environmental Health Perspectives 2021
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8278985/
https://ncbi.nlm.nih.gov/pubmed/34259569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/EHP8580
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