טוען...
Paternal MTHFR deficiency leads to hypomethylation of young retrotransposons and reproductive decline across two successive generations
5,10-Methylenetetrahydrofolate reductase (MTHFR) is a crucial enzyme in the folate metabolic pathway with a key role in generating methyl groups. As MTHFR deficiency impacts male fertility and sperm DNA methylation, there is the potential for epimutations to be passed to the next generation. Here, w...
שמור ב:
| הוצא לאור ב: | Development |
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| Main Authors: | , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
The Company of Biologists Ltd
2021
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8276981/ https://ncbi.nlm.nih.gov/pubmed/34128976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.199492 |
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