Betaine is accumulated via transient choline dehydrogenase activation during mouse oocyte meiotic maturation

Betaine (N,N,N-trimethylglycine) plays key roles in mouse eggs and preimplantation embryos first in a novel mechanism of cell volume regulation and second as a major methyl donor in blastocysts, but its origin is unknown. Here, we determined that endogenous betaine was present at low levels in germi...

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書目詳細資料
發表在:J Biol Chem
Main Authors: McClatchie, Taylor, Meredith, Megan, Ouédraogo, Mariame O., Slow, Sandy, Lever, Michael, Mann, Mellissa R. W., Zeisel, Steven H., Trasler, Jacquetta M., Baltz, Jay M.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2017
主題:
Developmental Biology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5566531/
https://ncbi.nlm.nih.gov/pubmed/28663368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.803080
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