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Patient-Specific 3-Dimensional Model of Smooth Muscle Cell and Extracellular Matrix Dysfunction for the Study of Aortic Aneurysms

INTRODUCTION: Abdominal aortic aneurysms (AAAs) are associated with overall high mortality in case of rupture. Since the pathophysiology is unclear, no adequate pharmacological therapy exists. Smooth muscle cells (SMCs) dysfunction and extracellular matrix (ECM) degradation have been proposed as und...

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Detalhes bibliográficos
Publicado no:J Endovasc Ther
Main Authors: Bogunovic, Natalija, Meekel, Jorn P., Majolée, Jisca, Hekhuis, Marije, Pyszkowski, Jakob, Jockenhövel, Stefan, Kruse, Magnus, Riesebos, Elise, Micha, Dimitra, Blankensteijn, Jan D., Hordijk, Peter L., Ghazanfari, Samaneh, Yeung, Kak K.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8276336/
https://ncbi.nlm.nih.gov/pubmed/33902345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/15266028211009272
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