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Impaired smooth muscle cell contractility as a novel concept of abdominal aortic aneurysm pathophysiology

Ruptured abdominal aortic aneurysms (AAA) are associated with overall mortality rates up to 90%. Despite extensive research, mechanisms leading to AAA formation and advancement are still poorly understood. Smooth muscle cells (SMC) are predominant in the aortic medial layer and maintain the wall str...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bogunovic, Natalija, Meekel, Jorn P., Micha, Dimitra, Blankensteijn, Jan D., Hordijk, Peter L., Yeung, Kak K.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497672/
https://ncbi.nlm.nih.gov/pubmed/31048749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43322-3
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