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Coordinated Cut and Bypass: Replication of Interstrand Crosslink-Containing DNA

DNA interstrand crosslinks (ICLs) are covalently bound DNA lesions, which are commonly induced by chemotherapeutic drugs, such as cisplatin and mitomycin C or endogenous byproducts of metabolic processes. This type of DNA lesion can block ongoing RNA transcription and DNA replication and thus cause...

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Bibliografiske detaljer
Udgivet i:Front Cell Dev Biol
Main Authors: Li, Qiuzhen, Dudás, Kata, Tick, Gabriella, Haracska, Lajos
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8275186/
https://ncbi.nlm.nih.gov/pubmed/34262911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.699966
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