Exploring New Scaffolds for the Dual Inhibition of HIV-1 RT Polymerase and Ribonuclease Associated Functions

Current therapeutic protocols for the treatment of HIV infection consist of the combination of diverse anti-retroviral drugs in order to reduce the selection of resistant mutants and to allow for the use of lower doses of each single agent to reduce toxicity. However, avoiding drugs interactions and...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Meleddu, Rita, Corona, Angela, Distinto, Simona, Cottiglia, Filippo, Deplano, Serenella, Sequeira, Lisa, Secci, Daniela, Onali, Alessia, Sanna, Erica, Esposito, Francesca, Cirone, Italo, Ortuso, Francesco, Alcaro, Stefano, Tramontano, Enzo, Mátyus, Péter, Maccioni, Elias
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8270338/
https://ncbi.nlm.nih.gov/pubmed/34201561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26133821
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