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Monosomy 3 Is Linked to Resistance to MEK Inhibitors in Uveal Melanoma

The use of MEK inhibitors in the therapy of uveal melanoma (UM) has been investigated widely but has failed to show benefits in clinical trials due to fast acquisition of resistance. In this study, we investigated a variety of therapeutic compounds in primary-derived uveal melanoma cell lines and fo...

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Dades bibliogràfiques
Publicat a:Int J Mol Sci
Autors principals: Mergener, Svenja, Siveke, Jens T., Peña-Llopis, Samuel
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8269285/
https://ncbi.nlm.nih.gov/pubmed/34201614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22136727
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