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Structural and Drug Targeting Insights on Mutant p53

SIMPLE SUMMARY: The tumor suppressor protein p53 is frequently mutated in human cancers, and its reactivation represents an encouraging hope for precision anticancer therapy. Despite this, the clinical use of compounds capable of restoring the wild-type-like function to mutant p53 (mutp53) is not ye...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Gomes, Ana Sara, Ramos, Helena, Inga, Alberto, Sousa, Emília, Saraiva, Lucília
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8268744/
https://ncbi.nlm.nih.gov/pubmed/34283062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13133344
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