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Structural and Drug Targeting Insights on Mutant p53

SIMPLE SUMMARY: The tumor suppressor protein p53 is frequently mutated in human cancers, and its reactivation represents an encouraging hope for precision anticancer therapy. Despite this, the clinical use of compounds capable of restoring the wild-type-like function to mutant p53 (mutp53) is not ye...

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Bibliographic Details
Published in:Cancers (Basel)
Main Authors: Gomes, Ana Sara, Ramos, Helena, Inga, Alberto, Sousa, Emília, Saraiva, Lucília
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8268744/
https://ncbi.nlm.nih.gov/pubmed/34283062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13133344
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