T Cell-Intrinsic CDK6 Is Dispensable for Anti-Viral and Anti-Tumor Responses In Vivo

The cyclin-dependent kinase 6 (CDK6) regulates the transition through the G1-phase of the cell cycle, but also acts as a transcriptional regulator. As such CDK6 regulates cell survival or cytokine secretion together with STATs, AP-1 or NF-κB. In the hematopoietic system, CDK6 regulates T cell develo...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Klein, Klara, Witalisz-Siepracka, Agnieszka, Gotthardt, Dagmar, Agerer, Benedikt, Locker, Felix, Grausenburger, Reinhard, Knab, Vanessa Maria, Bergthaler, Andreas, Sexl, Veronika
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8264666/
https://ncbi.nlm.nih.gov/pubmed/34248938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.650977
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